FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 2-oxoglutarate metabolic process ID (Ontology) GO:0006103 (Gene Ontology)
Definition The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.[ ISBN:0198506732 ]
Also Known As"2-ketoglutarate metabolic process" ; "2-ketoglutarate metabolism" ; "2-oxoglutarate metabolism" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 2-oxoglutarate metabolic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | 2-oxoglutarate metabolic process
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  carboxylic acid metabolic process
   |__dicarboxylic acid metabolic process
       |__2-oxoglutarate metabolic process  11 rec.
           |__2-oxoglutarate decarboxylation to succinyl-CoA 7 rec.
           |__acetyl-CoA assimilation pathway
           |__mixed acid fermentation
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Is a dicarboxylic acid metabolic process
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Synonyms
  • "2-ketoglutarate metabolic process" EXACT
    "2-ketoglutarate metabolism" EXACT
    "2-oxoglutarate metabolism" EXACT
    "alpha-ketoglutarate metabolic process" EXACT
    "alpha-ketoglutarate metabolism" EXACT
    "alpha-oxoglutarate metabolic process" EXACT
    "alpha-oxoglutarate metabolism" EXACT
Secondary IDs
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Reactome:R-HSA-2978092 "Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate"
Reactome:R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"