FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term DNA replication initiation ID (Ontology) GO:0006270 (Gene Ontology)
Definition The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.[ PubMed:28209641 ]
Also Known As "DNA-dependent DNA replication initiation"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 DNA replication initiation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | DNA replication initiation       --
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DNA replication
 |__DNA-templated DNA replication__
nucleic acid metabolic process     |
 |__DNA metabolic process__________|
                                   DNA replication initiation  32 rec.
                                    |__cell cycle DNA replication initiation 5 rec.
                                    |   |__bacterial-type DNA replication initiation
                                    |   |__nuclear cell cycle DNA replication initiation(+) 5 rec.
                                    |__regulation of DNA-templated DNA replication initiation 4 rec.
                                        |__negative regulation of DNA-templated DNA replication initiation(+)
                                        |__positive regulation of DNA-templated DNA replication initiation(+)
                                        |__regulation of initiation of premeiotic DNA replication(+)
                                        |__regulation of mitotic DNA replication initiation(+)
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Is a DNA metabolic process
Part of DNA-templated DNA replication
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Synonyms
  • "DNA endoreduplication initiation" NARROW
    "DNA re-replication initiation" NARROW
    "DNA-dependent DNA replication initiation" EXACT
Secondary IDs
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Reactome:R-HSA-68952 "DNA replication initiation"
Reactome:R-HSA-68962 "Activation of the pre-replicative complex"