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| Term | lagging strand elongation | ID (Ontology) | GO:0006273 (Gene Ontology) | |||||||||||
| Definition | The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.[ ISBN:0815316194 ] | |||||||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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DNA-templated DNA replication__ DNA strand elongation__________| DNA strand elongation involved in DNA replication |__lagging strand elongation 5 rec. |__DNA replication, Okazaki fragment processing 2 rec. | |__Okazaki fragment processing involved in mitotic DNA replication 1 rec. |__lagging strand initiation |__mitotic DNA replication lagging strand elongation |
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| Is a | DNA strand elongation involved in DNA replication | ||
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