FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term base-excision repair ID (Ontology) GO:0006284 (Gene Ontology)
Definition In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.[ ISBN:0815316194 ]
Also Known As "BER"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 base-excision repair (all annotations which use CV term, excluding "NOT" statements)
     involved_in | base-excision repair       --
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DNA metabolic process__
DNA damage response____|
                       DNA repair
                        |__base-excision repair  15 rec.
                            |__base-excision repair, AP site formation 3 rec.
                            |   |__base-excision repair, AP site formation via deaminated base removal
                            |   |__depurination
                            |   |__depyrimidination
                            |__base-excision repair, gap-filling 2 rec.
                            |__regulation of base-excision repair
                            |   |__negative regulation of base-excision repair
                            |   |__positive regulation of base-excision repair
                            |__telomere maintenance via base-excision repair
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Reactome:R-HSA-73884 "Base Excision Repair"
Reactome:R-HSA-73930 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
Wikipedia:Base_excision_repair