FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term nucleotide-excision repair ID (Ontology) GO:0006289 (Gene Ontology)
Definition A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).[ PubMed:10197977 ]
Also Known As"NER" ; "pyrimidine-dimer repair, DNA damage excision"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 nucleotide-excision repair (all annotations which use CV term, excluding "NOT" statements)
     involved_in | nucleotide-excision repair
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
DNA metabolic process__
DNA damage response____|
                       DNA repair
                        |__nucleotide-excision repair  28 rec.
                            |__global genome nucleotide-excision repair
                            |__nucleotide-excision repair involved in interstrand cross-link repair 3 rec.
                            |__nucleotide-excision repair, DNA damage recognition 1 rec.
                            |   |__transcription-coupled nucleotide-excision repair, DNA damage recognition
                            |__nucleotide-excision repair, DNA gap filling 3 rec.
                            |__nucleotide-excision repair, preincision complex assembly 1 rec.
                            |__nucleotide-excision repair, preincision complex stabilization
                            |__pyrimidine dimer repair by nucleotide-excision repair
                            |__regulation of nucleotide-excision repair
                            |   |__regulation of transcription-coupled nucleotide-excision repair
                            |__transcription-coupled nucleotide-excision repair 1 rec.
                                |__regulation of transcription-coupled nucleotide-excision repair
                                |__transcription-coupled nucleotide-excision repair, DNA damage recognition
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a DNA repair
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "intrastrand cross-link repair" RELATED
    "NER" EXACT
    "pyrimidine-dimer repair, DNA damage excision" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-5696398 "Nucleotide Excision Repair"
Reactome:R-HSA-5696400 "Dual Incision in GG-NER"