FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term apoptotic DNA fragmentation ID (Ontology) GO:0006309 (Gene Ontology)
Definition The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.[ ISBN:0721639976 PubMed:15723341 PubMed:23379520 ]
Also Known As"DNA catabolic process during apoptosis" ; "DNA catabolism during apoptosis" ; "DNA fragmentation involved in apoptotic nuclear change" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 apoptotic DNA fragmentation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | apoptotic DNA fragmentation
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DNA metabolic process
 |__DNA catabolic process________________________________________________
cellular component disassembly involved in execution phase of apoptosis  |
 |__apoptotic nuclear changes____________________________________________|
nucleic acid catabolic process                                           |
 |__DNA catabolic process________________________________________________|
                                                                         apoptotic DNA fragmentation  18 rec.
                                                                          |__regulation of apoptotic DNA fragmentation
                                                                              |__negative regulation of apoptotic DNA fragmentation
                                                                              |__positive regulation of apoptotic DNA fragmentation
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Is a DNA catabolic process
Part of apoptotic nuclear changes
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Synonyms
  • "chromatinolysis" BROAD
    "DNA catabolic process during apoptosis" EXACT
    "DNA catabolism during apoptosis" EXACT
    "DNA fragmentation" BROAD
    "DNA fragmentation involved in apoptotic nuclear change" EXACT
    "endonucleolytic DNA catabolic process involved in apoptosis" EXACT
Secondary IDs
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Reactome:R-HSA-140342 "Apoptosis induced DNA fragmentation"