FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

transcription initiation at RNA polymerase II promoter

ID (Ontology)

GO:0006367 (Gene Ontology)

Definition

A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II.

Also Known As

"transcription initiation from Pol II promoter" ; "transcription initiation from RNA polymerase II promoter"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
transcription initiation at RNA polymerase II promoter (all annotations which use CV term, excluding "NOT" statements)
involved_in \| transcription initiation at RNA polymerase II promoter	--

Spanning Tree (Parents/Children)

DNA-templated transcription
 |__DNA-templated transcription initiation__
 |__transcription by RNA polymerase II______|
RNA biosynthetic process                    |
 |__DNA-templated transcription initiation__|
                                            transcription initiation at RNA polymerase II promoter  114 rec.
                                             |__regulation of transcription initiation by RNA polymerase II 20 rec.
                                             |   |__negative regulation of transcription initiation by RNA polymerase II(+) 1 rec.
                                             |   |__positive regulation of transcription initiation by RNA polymerase II(+) 9 rec.
                                             |   |__regulation of RNA polymerase II transcription preinitiation complex assembly(+) 4 rec.
                                             |   |__regulation of transcriptional start site selection at RNA polymerase II promoter 8 rec.
                                             |__RNA polymerase II preinitiation complex assembly 19 rec.
                                             |   |__regulation of RNA polymerase II transcription preinitiation complex assembly(+) 4 rec.
                                             |__RNA polymerase II transcription initiation surveillance 16 rec.
                                             |__transcription initiation-coupled chromatin remodeling 16 rec.
                                             |   |__positive regulation of gene expression via chromosomal CpG island demethylation
                                             |__transcription open complex formation at RNA polymerase II promoter 6 rec.
                                             |   |__regulation of transcription open complex formation at RNA polymerase II promoter
                                             |__transcriptional start site selection at RNA polymerase II promoter 9 rec.
                                                 |__regulation of transcriptional start site selection at RNA polymerase II promoter 8 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	DNA-templated transcription initiation
Part of	transcription by RNA polymerase II
Synonyms & Secondary IDs
Synonyms
	"transcription initiation from Pol II promoter" EXACT "transcription initiation from RNA polymerase II promoter" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-167161 "HIV Transcription Initiation" Reactome:R-HSA-2032785 "YAP1- and WWTR1 (TAZ)-stimulated gene expression" Reactome:R-HSA-350054 "Notch-HLH transcription pathway" Reactome:R-HSA-383280 "Nuclear Receptor transcription pathway" Reactome:R-HSA-73779 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" Reactome:R-HSA-75953 "RNA Polymerase II Transcription Initiation"