FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 7-methylguanosine mRNA capping ID (Ontology) GO:0006370 (Gene Ontology)
Definition The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively.[ PubMed:9266685 ]
Also Known As "5' mRNA capping" ; "5'-end mRNA processing" ; "mRNA capping"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 7-methylguanosine mRNA capping (all annotations which use CV term, excluding "NOT" statements)
     involved_in | 7-methylguanosine mRNA capping
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RNA processing
 |__mRNA processing________________
mRNA metabolic process             |
 |__mRNA processing________________|
RNA capping                        |
 |__7-methylguanosine RNA capping__|
                                   7-methylguanosine mRNA capping  5 rec.
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Is a mRNA processing
7-methylguanosine RNA capping
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Synonyms
  • "5' end capping" BROAD
    "5' mRNA capping" EXACT
    "5'-end mRNA processing" EXACT
    "5'-end processing" BROAD
    "mRNA capping" EXACT
Secondary IDs
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Reactome:R-HSA-72086 "mRNA Capping"