FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein folding ID (Ontology) GO:0006457 (Gene Ontology)
Definition The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein folding (all annotations which use CV term, excluding "NOT" statements)
     involved_in | protein folding       --
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Vocabulary search 
biological_process
 |__cellular process_______
gene expression            |
 |__protein maturation_____|
protein metabolic process  |
 |__protein maturation_____|
                           protein folding  149 rec.
                            |__'de novo' protein folding 3 rec.
                            |   |__'de novo' cotranslational protein folding 2 rec.
                            |   |__'de novo' post-translational protein folding
                            |__protein folding in endoplasmic reticulum 4 rec.
                            |   |__regulation of protein folding in endoplasmic reticulum
                            |__protein refolding 34 rec.
                            |   |__regulation of protein refolding(+)
                            |__regulation of protein folding
                                |__negative regulation of protein folding(+)
                                |__positive regulation of protein folding(+)
                                |__regulation of protein folding in endoplasmic reticulum
                                |__regulation of protein refolding(+)
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Is a cellular process
Part of protein maturation
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Synonyms
  • "alpha-tubulin folding" NARROW
    "beta-tubulin folding" NARROW
    "chaperone activity" RELATED
    "chaperonin ATPase activity" RELATED
    "chaperonin-mediated tubulin folding" NARROW
    "co-chaperone activity" RELATED
    "co-chaperonin activity" RELATED
    "glycoprotein-specific chaperone activity" RELATED
    "non-chaperonin molecular chaperone ATPase activity" RELATED
    "protein complex assembly, multichaperone pathway" RELATED
Secondary IDs
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Reactome:R-HSA-389960 "Formation of tubulin folding intermediates by CCT/TriC"
Reactome:R-HSA-390450 "Folding of actin by CCT/TriC"
Reactome:R-HSA-390466 "Chaperonin-mediated protein folding"
Reactome:R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
Wikipedia:Protein_folding