FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term SRP-dependent cotranslational protein targeting to membrane, translocation ID (Ontology) GO:0006616 (Gene Ontology)
Definition The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.[ ISBN:0716731363 ]
Also Known As"SRP-dependent cotranslational membrane targeting, translocation" ; "SRP-dependent cotranslational protein-membrane targeting, translocation" ; "translocation during SRP-dependent cotranslational protein targeting to membrane"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 SRP-dependent cotranslational protein targeting to membrane, translocation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | SRP-dependent cotranslational protein targeting to membrane, translocation       --
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
cotranslational protein targeting to membrane
 |__SRP-dependent cotranslational protein targeting to membrane__
intracellular protein transport                                  |
 |__intracellular protein transmembrane transport________________|
protein targeting to ER                                          |
 |__SRP-dependent cotranslational protein targeting to membrane__|
protein transmembrane transport                                  |
 |__intracellular protein transmembrane transport________________|
                                                                 SRP-dependent cotranslational protein targeting to membrane, translocation  13 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a intracellular protein transmembrane transport
Part of SRP-dependent cotranslational protein targeting to membrane
hide Synonyms & Secondary IDs
Synonyms
  • "ER translocation" BROAD
    "SRP-dependent cotranslational membrane targeting, translocation" EXACT
    "SRP-dependent cotranslational protein-membrane targeting, translocation" EXACT
    "translocation during SRP-dependent cotranslational protein targeting to membrane" EXACT
Secondary IDs
hide External Crossreferences & Linkouts