FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term post-translational protein targeting to endoplasmic reticulum membrane ID (Ontology) GO:0006620 (Gene Ontology)
Definition The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.[ ISBN:0716731363 ]
Also Known As"posttranslational endoplasmic reticulum membrane targeting" ; "posttranslational endoplasmic reticulum protein-membrane targeting" ; "posttranslational protein endoplasmic reticulum membrane targeting" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 post-translational protein targeting to endoplasmic reticulum membrane (all annotations which use CV term, excluding "NOT" statements)
     involved_in | post-translational protein targeting to endoplasmic reticulum membrane
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protein targeting
 |__protein targeting to membrane_______________________________
 |__protein targeting to ER_____________________________________|
establishment of protein localization to endoplasmic reticulum  |
 |__protein targeting to ER_____________________________________|
establishment of protein localization to membrane               |
 |__protein targeting to membrane_______________________________|
                                                                post-translational protein targeting to endoplasmic reticulum membrane  9 rec.
                                                                 |__post-translational protein targeting to membrane, docking
                                                                 |__post-translational protein targeting to membrane, translocation 6 rec.
                                                                     |__regulation of post-translational protein targeting to membrane, translocation(+)
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Is a protein targeting to membrane
protein targeting to ER
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Synonyms
  • "posttranslational endoplasmic reticulum membrane targeting" EXACT
    "posttranslational endoplasmic reticulum protein-membrane targeting" EXACT
    "posttranslational protein endoplasmic reticulum membrane targeting" EXACT
    "posttranslational protein targeting to endoplasmic reticulum membrane" EXACT
    "posttranslational protein targeting to ER membrane" EXACT
    "SRP-independent endoplasmic reticulum protein-membrane targeting" EXACT
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