FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

protein retention in ER lumen

ID (Ontology)

GO:0006621 (Gene Ontology)

Definition

The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.[ ISBN:0716731363 PubMed:12972550 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
protein retention in ER lumen (all annotations which use CV term, excluding "NOT" statements)
involved_in \| protein retention in ER lumen

Spanning Tree (Parents/Children)

protein localization to endoplasmic reticulum_____
maintenance of protein localization in organelle__|
                                                  maintenance of protein localization in endoplasmic reticulum
                                                   |__protein retention in ER lumen  3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	maintenance of protein localization in endoplasmic reticulum
Part of
Synonyms & Secondary IDs
Synonyms
	"maintenance of protein location in ER lumen" BROAD
Secondary IDs

External Crossreferences & Linkouts