FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term cholesterol biosynthetic process ID (Ontology) GO:0006695 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Also Known As"cholesterol anabolism" ; "cholesterol biosynthesis" ; "cholesterol formation" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 cholesterol biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | cholesterol biosynthetic process
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steroid biosynthetic process
 |__sterol biosynthetic process_____________
sterol metabolic process                    |
 |__cholesterol metabolic process___________|
 |__sterol biosynthetic process_____________|
alcohol biosynthetic process                |
 |__secondary alcohol biosynthetic process__|
secondary alcohol metabolic process         |
 |__cholesterol metabolic process___________|
 |__secondary alcohol biosynthetic process__|
                                            cholesterol biosynthetic process  3 rec.
                                             |__regulation of cholesterol biosynthetic process 1 rec.
                                                 |__negative regulation of cholesterol biosynthetic process
                                                 |__positive regulation of cholesterol biosynthetic process 1 rec.
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Is a cholesterol metabolic process
sterol biosynthetic process
secondary alcohol biosynthetic process
Part of
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Synonyms
  • "cholesterol anabolism" EXACT
    "cholesterol biosynthesis" EXACT
    "cholesterol formation" EXACT
    "cholesterol synthesis" EXACT
Secondary IDs
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MetaCyc:PWY66-3
MetaCyc:PWY66-341
MetaCyc:PWY66-4
Reactome:R-HSA-191273 "Cholesterol biosynthesis"