FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tetrahydrobiopterin biosynthetic process ID (Ontology) GO:0006729 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.[ ISBN:0198506732 ]
Also Known As"5,6,7,8-tetrahydrobiopterin biosynthetic process" ; "tetrahydrobiopterin anabolism" ; "tetrahydrobiopterin biosynthesis" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 tetrahydrobiopterin biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | tetrahydrobiopterin biosynthetic process
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biosynthetic process
 |__pteridine-containing compound biosynthetic process__
diol metabolic process                                  |
 |__diol biosynthetic process___________________________|
 |__tetrahydrobiopterin metabolic process_______________|
pteridine-containing compound metabolic process         |
 |__pteridine-containing compound biosynthetic process__|
 |__tetrahydrobiopterin metabolic process_______________|
polyol biosynthetic process                             |
 |__diol biosynthetic process___________________________|
                                                        tetrahydrobiopterin biosynthetic process  6 rec.
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Is a diol biosynthetic process
pteridine-containing compound biosynthetic process
tetrahydrobiopterin metabolic process
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Synonyms
  • "5,6,7,8-tetrahydrobiopterin biosynthetic process" EXACT
    "tetrahydrobiopterin anabolism" EXACT
    "tetrahydrobiopterin biosynthesis" EXACT
    "tetrahydrobiopterin formation" EXACT
    "tetrahydrobiopterin synthesis" EXACT
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