FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

heme biosynthetic process

ID (Ontology)

GO:0006783 (Gene Ontology)

Definition

The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.[ PubMed:11788607 ]

Also Known As

"haem biosynthesis" ; "haem biosynthetic process" ; "heme anabolism" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
heme biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
involved_in \| heme biosynthetic process	--

Spanning Tree (Parents/Children)

porphyrin-containing compound metabolic process
 |__porphyrin-containing compound biosynthetic process__
 |__heme metabolic process______________________________|
tetrapyrrole biosynthetic process                       |
 |__porphyrin-containing compound biosynthetic process__|
pigment metabolic process                               |
 |__heme metabolic process______________________________|
 |__pigment biosynthetic process________________________|
                                                        heme biosynthetic process  14 rec.
                                                         |__heme A biosynthetic process 3 rec.
                                                         |__heme B biosynthetic process
                                                         |__heme C biosynthetic process
                                                         |__heme O biosynthetic process
                                                         |__regulation of heme biosynthetic process
                                                         |   |__negative regulation of heme biosynthetic process
                                                         |   |__positive regulation of heme biosynthetic process
                                                         |__siroheme biosynthetic process

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	porphyrin-containing compound biosynthetic process heme metabolic process pigment biosynthetic process
Part of
Synonyms & Secondary IDs
Synonyms
	"haem biosynthesis" EXACT "haem biosynthetic process" EXACT "heme anabolism" EXACT "heme biosynthesis" EXACT "heme formation" EXACT "heme synthesis" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-189451 "Heme biosynthesis"