FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

phagocytosis, engulfment

ID (Ontology)

GO:0006911 (Gene Ontology)

Definition

The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.[ ISBN:0781735149 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
phagocytosis, engulfment (all annotations which use CV term, excluding "NOT" statements)
involved_in \| phagocytosis, engulfment

Spanning Tree (Parents/Children)

endocytosis
 |__phagocytosis__________________
membrane invagination             |
 |__plasma membrane invagination__|
                                  phagocytosis, engulfment  17 rec.
                                   |__cytoskeletal rearrangement involved in phagocytosis, engulfment 1 rec.
                                   |__engulfment of apoptotic cell 9 rec.
                                   |   |__regulation of engulfment of apoptotic cell(+)
                                   |__membrane reorganization involved in phagocytosis, engulfment
                                   |__regulation of phagocytosis, engulfment 1 rec.
                                       |__negative regulation of phagocytosis, engulfment(+)
                                       |__positive regulation of phagocytosis, engulfment(+) 1 rec.
                                       |__regulation of engulfment of apoptotic cell(+)

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	plasma membrane invagination
Part of	phagocytosis
Synonyms & Secondary IDs
Synonyms
	"phagosome biosynthesis" RELATED "phagosome formation" RELATED
Secondary IDs

External Crossreferences & Linkouts