FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term autophagy ID (Ontology) GO:0006914 (Gene Ontology)
Definition The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation.[ ISBN:0198547684 PubMed:11099404 PubMed:29455577 PubMed:9412464 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 autophagy (all annotations which use CV term, excluding "NOT" statements)
     involved_in | autophagy       --
 NOT | involved_in | autophagy       --
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metabolic process
 |__catabolic process_______________________
cellular process                            |
 |__process utilizing autophagic mechanism__|
                                            autophagy  229 rec.
                                             |__autophagy of mitochondrion 45 rec.
                                             |   |__micromitophagy
                                             |   |__mitophagy(+) 40 rec.
                                             |   |__mitophagy by internal vacuole formation
                                             |   |__regulation of autophagy of mitochondrion(+) 15 rec.
                                             |__autophagy of peroxisome 7 rec.
                                             |   |__micropexophagy
                                             |   |__pexophagy 7 rec.
                                             |__chaperone-mediated autophagy
                                             |   |__chaperone-mediated autophagy translocation complex assembly
                                             |   |__protein targeting to lysosome involved in chaperone-mediated autophagy
                                             |   |__regulation of chaperone-mediated autophagy(+)
                                             |__crinophagy 11 rec.
                                             |   |__secretory granule-lysosome fusion 8 rec.
                                             |__macroautophagy 166 rec.
                                             |   |__aggrephagy(+) 4 rec.
                                             |   |__amphisome-lysosome fusion
                                             |   |__autophagosome maturation(+) 32 rec.
                                             |   |__autophagosome organization(+) 44 rec.
                                             |   |__autophagosome-endosome fusion
                                             |   |__autophagosome-lysosome fusion 12 rec.
                                             |   |__ferritinophagy
                                             |   |__glycophagy 13 rec.
                                             |   |__lipophagy(+) 10 rec.
                                             |   |__lysophagy
                                             |   |__mitophagy(+) 40 rec.
                                             |   |__nucleophagy(+) 16 rec.
                                             |   |__pexophagy 7 rec.
                                             |   |__proteaphagy
                                             |   |__regulation of macroautophagy(+) 65 rec.
                                             |   |__reticulophagy(+) 18 rec.
                                             |   |__ribophagy 1 rec.
                                             |   |__xenophagy(+)
                                             |__microautophagy 12 rec.
                                             |   |__late endosomal microautophagy 1 rec.
                                             |   |__microlipophagy(+)
                                             |   |__micromitophagy
                                             |   |__micropexophagy
                                             |   |__piecemeal microautophagy of the nucleus 11 rec.
                                             |__protein targeting to vacuole involved in autophagy
                                             |   |__protein targeting to lysosome involved in chaperone-mediated autophagy
                                             |__regulation of autophagy 115 rec.
                                                 |__negative regulation of autophagy(+) 31 rec.
                                                 |__positive regulation of autophagy(+) 65 rec.
                                                 |__regulation of autophagy of mitochondrion(+) 15 rec.
                                                 |__regulation of chaperone-mediated autophagy(+)
                                                 |__regulation of macroautophagy(+) 65 rec.
                                                 |__regulation of microlipophagy
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Is a catabolic process
process utilizing autophagic mechanism
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Reactome:R-HSA-9612973 "Autophagy"
Wikipedia:Autophagy_(cellular)