FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

ID (Ontology)

GO:0007188 (Gene Ontology)

Definition

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP).[ ISBN:0815316194 ]

Also Known As

"adenylate cyclase-modulating GPCR signaling pathway" ; "G protein signaling, coupled to cAMP nucleotide second messenger" ; "G protein signaling, coupled to cyclic AMP nucleotide second messenger" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
adenylate cyclase-modulating G protein-coupled receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)
involved_in \| adenylate cyclase-modulating G protein-coupled receptor signaling pathway
NOT \| involved_in \| adenylate cyclase-modulating G protein-coupled receptor signaling pathway

Spanning Tree (Parents/Children)

  signal transduction
   |__G protein-coupled receptor signaling pathway
       |__adenylate cyclase-modulating G protein-coupled receptor signaling pathway  66 rec.
           |__adenylate cyclase-activating G protein-coupled receptor signaling pathway 44 rec.
           |   |__adenylate cyclase-activating adrenergic receptor signaling pathway(+) 8 rec.
           |   |__adenylate cyclase-activating dopamine receptor signaling pathway 4 rec.
           |   |__adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway
           |   |__adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
           |   |__adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway(+)
           |   |__adenylate cyclase-activating serotonin receptor signaling pathway 1 rec.
           |   |__ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway
           |   |__regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway(+) 2 rec.
           |__adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 13 rec.
               |__adenylate cyclase-inhibiting adrenergic receptor signaling pathway(+) 2 rec.
               |__adenylate cyclase-inhibiting dopamine receptor signaling pathway(+)
               |__adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 2 rec.
               |__adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
               |__adenylate cyclase-inhibiting opioid receptor signaling pathway(+)
               |__adenylate cyclase-inhibiting serotonin receptor signaling pathway 2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	G protein-coupled receptor signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"adenylate cyclase-modulating GPCR signaling pathway" EXACT "G protein signaling, coupled to cAMP nucleotide second messenger" EXACT "G protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT "G protein signalling, coupled to cAMP nucleotide second messenger" EXACT "G protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT "G-protein signaling, coupled to cAMP nucleotide second messenger" EXACT "G-protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT "G-protein signalling, coupled to cAMP nucleotide second messenger" EXACT "G-protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT "GPCR signaling pathway via cAMP second messenger" EXACT "GPCR signaling pathway via modulation of adenylate cyclase activity" EXACT
Secondary IDs

External Crossreferences & Linkouts