FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

ID (Ontology)

GO:0007193 (Gene Ontology)

Definition

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP).[ ISBN:0815316194 ]

Also Known As

"adenylate cyclase-inhibiting GPCR signaling pathway" ; "G protein signaling, adenylate cyclase inhibiting pathway" ; "G protein signaling, adenylyl cyclase inhibiting pathway" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)
involved_in \| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

Spanning Tree (Parents/Children)

  G protein-coupled receptor signaling pathway
   |__adenylate cyclase-modulating G protein-coupled receptor signaling pathway
       |__adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  13 rec.
           |__adenylate cyclase-inhibiting adrenergic receptor signaling pathway 2 rec.
           |   |__regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway
           |__adenylate cyclase-inhibiting dopamine receptor signaling pathway
           |   |__regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway(+)
           |__adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 2 rec.
           |__adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
           |__adenylate cyclase-inhibiting opioid receptor signaling pathway
           |   |__regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway(+)
           |__adenylate cyclase-inhibiting serotonin receptor signaling pathway 2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"adenylate cyclase-inhibiting GPCR signaling pathway" EXACT "G protein signaling, adenylate cyclase inhibiting pathway" EXACT "G protein signaling, adenylyl cyclase inhibiting pathway" EXACT "G protein signalling, adenylate cyclase inhibiting pathway" EXACT "G protein signalling, adenylyl cyclase inhibiting pathway" EXACT "G-protein signaling, adenylate cyclase inhibiting pathway" EXACT "G-protein signaling, adenylyl cyclase inhibiting pathway" EXACT "G-protein signalling, adenylate cyclase inhibiting pathway" EXACT "G-protein signalling, adenylyl cyclase inhibiting pathway" EXACT "GPCR signaling pathway via inhibition of adenylate cyclase activity" EXACT "inhibition of adenylate cyclase activity by G-protein signaling pathway" RELATED
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-170670 "Adenylate cyclase inhibitory pathway"