FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term patched ligand maturation ID (Ontology) GO:0007225 (Gene Ontology)
Definition The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.[ PubMed:15057936 ]
Also Known As"hh protein processing"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 patched ligand maturation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | patched ligand maturation       --
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hormone metabolic process_______________________
signaling receptor ligand precursor processing__|
                                                peptide hormone processing
                                                 |__patched ligand maturation  3 rec.
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Is a peptide hormone processing
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Synonyms
  • "Hedgehog protein processing" NARROW
    "hh protein processing" EXACT
    "patched ligand processing" RELATED
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