FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

chemokine activity

ID (Ontology)

GO:0008009 (Gene Ontology)

Definition

The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.[ PubMed:12183377 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
chemokine activity (all annotations which use CV term, excluding "NOT" statements)
enables \| chemokine activity

Spanning Tree (Parents/Children)

G protein-coupled receptor binding
 |__chemokine receptor binding__
cytokine receptor binding       |
 |__chemokine receptor binding__|
receptor ligand activity        |
 |__cytokine activity___________|
                                chemokine activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cytokine activity chemokine receptor binding
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts