FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tRNA processing ID (Ontology) GO:0008033 (Gene Ontology)
Definition The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.[ PubMed:12533506 ]
Also Known As"tRNA maturation"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 tRNA processing (all annotations which use CV term, excluding "NOT" statements)
     involved_in | tRNA processing
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gene expression
 |__RNA processing__________
RNA metabolic process       |
 |__tRNA metabolic process__|
RNA biosynthetic process    |
 |__RNA processing__________|
primary metabolic process   |
 |__RNA processing__________|
                            tRNA processing  106 rec.
                             |__mitochondrial tRNA processing 17 rec.
                             |   |__mitochondrial tRNA 3'-end processing 2 rec.
                             |   |__mitochondrial tRNA 5'-end processing 4 rec.
                             |   |__mitochondrial tRNA modification(+) 12 rec.
                             |__regulation of tRNA processing 1 rec.
                             |   |__negative regulation of tRNA processing
                             |   |__positive regulation of tRNA processing(+) 1 rec.
                             |   |__regulation of tRNA methylation(+)
                             |__tRNA 3'-end processing 3 rec.
                             |   |__mitochondrial tRNA 3'-end processing 2 rec.
                             |   |__tRNA 3'-terminal CCA addition 1 rec.
                             |__tRNA 5'-end processing 17 rec.
                             |   |__mitochondrial tRNA 5'-end processing 4 rec.
                             |   |__tRNA 5'-leader removal 10 rec.
                             |__tRNA modification 73 rec.
                             |   |__archaeosine-tRNA biosynthetic process
                             |   |__charged-tRNA amino acid modification(+) 2 rec.
                             |   |__cyclic threonylcarbamoyladenosine biosynthetic process
                             |   |__mitochondrial tRNA modification(+) 12 rec.
                             |   |__regulation of translational initiation by tRNA modification
                             |   |__tRNA acetylation 1 rec.
                             |   |__tRNA adenosine deamination to inosine
                             |   |__tRNA dihydrouridine synthesis 1 rec.
                             |   |__tRNA methylation(+) 25 rec.
                             |   |__tRNA methylthiolation 1 rec.
                             |   |__tRNA pseudouridine synthesis(+) 6 rec.
                             |   |__tRNA seleno-modification
                             |   |__tRNA thio-modification(+) 6 rec.
                             |   |__tRNA threonylcarbamoyladenosine modification(+) 4 rec.
                             |   |__tRNA wobble base modification(+) 25 rec.
                             |   |__wybutosine biosynthetic process
                             |__tRNA splicing, via endonucleolytic cleavage and ligation 10 rec.
                                 |__tRNA exon ligation
                                 |__tRNA-type intron splice site recognition and cleavage 3 rec.
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Is a RNA processing
tRNA metabolic process
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Synonyms
  • "tRNA maturation" EXACT
Secondary IDs
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Reactome:R-HSA-72306 "tRNA processing"