FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term intracellular protein localization ID (Ontology) GO:0008104 (Gene Ontology)
Definition Any process in which a protein is transported to, or maintained in, a specific location.
Also Known As "cellular protein localisation" ; "cellular protein localization" ; "protein localisation"
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      71
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 intracellular protein localization (all annotations which use CV term, excluding "NOT" statements)      71
     involved_in | intracellular protein localization      71
Spanning Tree (Parents/Children)
Only view relationship:
  localization
   |__macromolecule localization
       |__intracellular protein localization  707 rec.
           |__apical protein localization 18 rec.
           |__asymmetric protein localization involved in cell fate determination 18 rec.
           |   |__regulation of asymmetric protein localization involved in cell fate determination(+) 1 rec.
           |__basal protein localization 11 rec.
           |__intracellular protein transport 261 rec.
           |   |__endocytosed protein transport to vacuole
           |   |__endosome to plasma membrane protein transport(+) 5 rec.
           |   |__establishment of protein localization to mast cell secretory granule(+)
           |   |__establishment of protein localization to T cell secretory granule(+)
           |   |__intracellular protein transmembrane transport(+) 30 rec.
           |   |__microtubule polymerization based protein transport(+)
           |   |__misfolded protein transport(+)
           |   |__neurotransmitter receptor transport, postsynaptic endosome to lysosome 1 rec.
           |   |__polyubiquitinated protein transport(+)
           |   |__protein exit from endoplasmic reticulum(+) 7 rec.
           |   |__protein export from nucleus(+) 19 rec.
           |   |__protein import into nucleus(+) 59 rec.
           |   |__protein import into peroxisome membrane 4 rec.
           |   |__protein targeting to vacuole(+) 17 rec.
           |   |__protein transport along microtubule(+) 6 rec.
           |   |__protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 6 rec.
           |   |__protein transport within lipid bilayer(+)
           |   |__protein-DNA complex transport
           |   |__regulation of intracellular protein transport(+) 23 rec.
           |__maintenance of protein location 21 rec.
           |   |__maintenance of protein location in cell(+) 15 rec.
           |   |__maintenance of protein location in extracellular region 3 rec.
           |__pole plasm protein localization 12 rec.
           |__positive regulation of transcription by transcription factor localization 2 rec.
           |__protein import into peroxisome matrix, docking 5 rec.
           |__protein insertion into membrane 57 rec.
           |   |__protein insertion into ER membrane(+) 15 rec.
           |   |__protein insertion into membrane raft(+)
           |   |__protein insertion into mitochondrial membrane(+) 42 rec.
           |   |__protein insertion into plasma membrane(+)
           |__protein localization involved in acrosome reaction
           |__protein localization involved in auxin polar transport
           |__protein localization involved in establishment of planar polarity 8 rec.
           |__protein localization to axon
           |   |__protein localization to juxtaparanode region of axon
           |   |__protein localization to paranode region of axon
           |__protein localization to bud neck
           |__protein localization to cell division site 2 rec.
           |   |__protein localization to actomyosin contractile ring(+)
           |   |__protein localization to cell division site after cytokinesis
           |   |__protein localization to cell division site involved in mitotic actomyosin contractile ring assembly(+)
           |   |__protein localization to cleavage furrow(+) 2 rec.
           |   |__protein localization to division septum
           |   |__protein localization to equatorial microtubule organizing center
           |   |__protein localization to medial cortex(+)
           |   |__regulation of protein localization to cell division site(+)
           |__protein localization to cell junction 14 rec.
           |   |__protein localization to cell-cell junction(+) 6 rec.
           |   |__protein localization to synapse(+) 9 rec.
           |__protein localization to cell leading edge 1 rec.
           |   |__regulation of protein localization to cell leading edge(+)
           |__protein localization to cell periphery 68 rec.
           |   |__endocytosis, site selection
           |   |__neurotransmitter receptor transport to plasma membrane(+) 2 rec.
           |   |__protein localization to basolateral plasma membrane(+)
           |   |__protein localization to cell cortex(+) 8 rec.
           |   |__protein localization to cell wall
           |   |__protein localization to ciliary membrane(+) 1 rec.
           |   |__protein localization to cleavage furrow(+) 2 rec.
           |   |__protein localization to microvillus membrane
           |   |__protein localization to outer membrane
           |   |__protein localization to plasma membrane(+) 58 rec.
           |   |__protein localization to plasma membrane of cell tip
           |   |__protein localization to plasma membrane raft(+)
           |   |__protein localization to postsynaptic membrane(+) 3 rec.
           |   |__protein localization to presynaptic membrane
           |   |__protein localization to spore cell wall(+)
           |   |__protein transport out of plasma membrane raft
           |   |__regulation of protein localization to cell periphery(+) 14 rec.
           |__protein localization to cell surface 7 rec.
           |   |__regulation of protein localization to cell surface(+) 3 rec.
           |__protein localization to cell tip
           |   |__protein localization to cell cortex of cell tip(+)
           |   |__protein localization to growing cell tip(+)
           |   |__protein localization to mating projection tip
           |   |__protein localization to non-growing cell tip(+)
           |   |__protein localization to plasma membrane of cell tip
           |   |__protein transport along microtubule to cell tip
           |   |__regulation of protein localization to cell tip(+)
           |__protein localization to cytosolic proteasome complex
           |__protein localization to membrane 94 rec.
           |   |__guanylate kinase-associated protein clustering
           |   |__maintenance of protein location in membrane(+)
           |   |__neurotransmitter receptor transport to plasma membrane(+) 2 rec.
           |   |__postsynaptic density protein 95 clustering(+)
           |   |__protein import into chloroplast thylakoid membrane
           |   |__protein import into peroxisome membrane 4 rec.
           |   |__protein localization to basolateral plasma membrane(+)
           |   |__protein localization to ciliary membrane(+) 1 rec.
           |   |__protein localization to cleavage furrow(+) 2 rec.
           |   |__protein localization to Golgi membrane 4 rec.
           |   |__protein localization to membrane raft(+)
           |   |__protein localization to microvillus membrane
           |   |__protein localization to nuclear inner membrane 3 rec.
           |   |__protein localization to outer membrane
           |   |__protein localization to plasma membrane(+) 58 rec.
           |   |__protein localization to plasma membrane of cell tip
           |   |__protein localization to postsynaptic membrane(+) 3 rec.
           |   |__protein localization to presynaptic membrane
           |   |__protein localization to prospore membrane(+)
           |   |__protein localization to vacuolar membrane(+)
           |   |__protein transport out of plasma membrane raft
           |   |__receptor clustering(+) 12 rec.
           |   |__regulation of protein localization to membrane(+) 18 rec.
           |   |__t-SNARE clustering(+)
           |__protein localization to microvillus
           |   |__protein localization to microvillus membrane
           |__protein localization to myelin sheath abaxonal region
           |__protein localization to organelle 291 rec.
           |   |__endocytic hemoglobin import into cell
           |   |__maintenance of protein localization in organelle(+) 7 rec.
           |   |__protein insertion into ER membrane(+) 15 rec.
           |   |__protein localization to chloroplast(+)
           |   |__protein localization to chromosome(+) 17 rec.
           |   |__protein localization to cilium(+) 13 rec.
           |   |__protein localization to cytoplasmic stress granule
           |   |__protein localization to cytoskeleton(+) 15 rec.
           |   |__protein localization to endoplasmic reticulum(+) 6 rec.
           |   |__protein localization to endosome(+) 3 rec.
           |   |__protein localization to Golgi apparatus(+) 10 rec.
           |   |__protein localization to lipid droplet 3 rec.
           |   |__protein localization to M-band 1 rec.
           |   |__protein localization to mitochondrion(+) 93 rec.
           |   |__protein localization to nucleus(+) 72 rec.
           |   |__protein localization to P-body
           |   |__protein localization to peroxisome(+) 18 rec.
           |   |__protein localization to phagocytic vesicle(+)
           |   |__protein localization to postsynaptic specialization membrane(+) 1 rec.
           |   |__protein localization to secretory granule(+)
           |   |__protein localization to vacuole(+) 24 rec.
           |   |__protein transmembrane import into intracellular organelle(+) 14 rec.
           |   |__ubiquitin-dependent endocytosis(+) 3 rec.
           |__protein localization to perinuclear region of cytoplasm
           |__protein localization to phagophore assembly site 5 rec.
           |__protein localization to rhabdomere 7 rec.
           |__protein localization to somatodendritic compartment
           |__protein localization to trailing edge
           |   |__protein localization to uropod
           |__protein transport 398 rec.
           |   |__apolipoprotein E recycling
           |   |__cytosol to ERGIC protein transport
           |   |__endocytic hemoglobin import into cell
           |   |__glycoprotein transport
           |   |__Golgi to plasma membrane protein transport(+) 19 rec.
           |   |__intracellular protein transport 261 rec.
           |   |__lactoferrin transport
           |   |__lipoprotein transport(+) 2 rec.
           |   |__microtubule-based protein transport(+) 6 rec.
           |   |__neurotransmitter receptor transport(+) 3 rec.
           |   |__opsin transport
           |   |__protein import(+)
           |   |__protein secretion(+) 68 rec.
           |   |__protein transmembrane transport(+) 77 rec.
           |   |__protein transport across periplasmic space
           |   |__protein transport to mating projection actin fusion focus
           |   |__protein transport within extracellular region
           |   |__regulation of protein transport(+) 54 rec.
           |   |__symbiont intracellular protein transport in host(+)
           |   |__transferrin transport
           |   |__ubiquitin-dependent endocytosis(+) 3 rec.
           |__regulation of protein localization 106 rec.
           |   |__negative regulation of protein localization(+) 14 rec.
           |   |__positive regulation of protein localization(+) 51 rec.
           |   |__regulation of asymmetric protein localization involved in cell fate determination(+) 1 rec.
           |   |__regulation of establishment of protein localization(+) 58 rec.
           |   |__regulation of protein localization to cell division site(+)
           |   |__regulation of protein localization to cell leading edge(+)
           |   |__regulation of protein localization to cell periphery(+) 14 rec.
           |   |__regulation of protein localization to cell surface(+) 3 rec.
           |   |__regulation of protein localization to cell tip(+)
           |   |__regulation of protein localization to cell-cell junction(+)
           |   |__regulation of protein localization to centrosome(+)
           |   |__regulation of protein localization to chromatin(+) 2 rec.
           |   |__regulation of protein localization to chromosome, telomeric region(+)
           |   |__regulation of protein localization to cilium(+)
           |   |__regulation of protein localization to endoplasmic reticulum(+) 1 rec.
           |   |__regulation of protein localization to endosome(+) 2 rec.
           |   |__regulation of protein localization to kinetochore(+) 1 rec.
           |   |__regulation of protein localization to lysosome(+)
           |   |__regulation of protein localization to membrane(+) 18 rec.
           |   |__regulation of protein localization to microtubule(+)
           |   |__regulation of protein localization to mitochondrion(+) 3 rec.
           |   |__regulation of protein localization to nucleus(+) 13 rec.
           |   |__regulation of protein localization to phagocytic vesicle(+)
           |   |__regulation of protein localization to spindle pole body(+) 1 rec.
           |   |__regulation of protein localization to synapse(+) 1 rec.
           |__regulation of translation by machinery localization
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Is a macromolecule localization
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Synonyms
  • "asymmetric protein localisation" RELATED
    "asymmetric protein localization" RELATED
    "cellular protein localisation" EXACT
    "cellular protein localization" EXACT
    "channel localizer activity" NARROW
    "establishment and maintenance of asymmetric protein localization" RELATED
    "establishment and maintenance of protein localization" RELATED
    "protein localisation" EXACT
    "protein localization" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-9609507 "Protein localization"