FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term alcohol dehydrogenase (NADP+) activity ID (Ontology) GO:0008106 (Gene Ontology)
Definition Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or ketone + NADPH + H+.[ EC:1 ]
Also Known As "alcohol:NADP dehydrogenase activity" ; "aldehyde reductase (NADPH) activity" ; "NADP-aldehyde reductase activity"
Comment
Links to External Ontologies
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 alcohol dehydrogenase (NADP+) activity (all annotations which use CV term, excluding "NOT" statements)       2      2
     enables | alcohol dehydrogenase (NADP+) activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
   |__alcohol dehydrogenase [NAD(P)+] activity
       |__alcohol dehydrogenase (NADP+) activity  28 rec.
           |__2-methylbutanal reductase (NADPH) activity
           |__3-methylbutanal reductase (NADPH) activity
           |__11-cis-retinol dehydrogenase (NADP+) activity 1 rec.
           |__aldose reductase (NADPH) activity 9 rec.
           |   |__D-xylose reductase (NADPH) activity
           |   |__L-arabinose reductase (NADPH) activity
           |__all-trans-retinol dehydrogenase (NADP+) activity 10 rec.
           |__carbonyl reductase (NADPH) activity 5 rec.
           |__pyridoxine 4-dehydrogenase (NADP+) activity
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Is a alcohol dehydrogenase [NAD(P)+] activity
Part of
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Synonyms
  • "alcohol:NADP dehydrogenase activity" EXACT
    "aldehyde reductase (NADPH) activity" EXACT
    "NADP-aldehyde reductase activity" EXACT
Secondary IDs
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EC:1.1.1.2
MetaCyc:ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN
Reactome:R-HSA-192033 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one"
Reactome:R-HSA-192036 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol"
Reactome:R-HSA-192067 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one"
Reactome:R-HSA-192160 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol"
Reactome:R-HSA-193746 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one"
Reactome:R-HSA-193755 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one"
Reactome:R-HSA-193758 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol"
Reactome:R-HSA-193781 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol"
Reactome:R-HSA-193800 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol"
Reactome:R-HSA-193821 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one"
Reactome:R-HSA-193824 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one"
Reactome:R-HSA-193841 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol"
Reactome:R-HSA-198845 "CYB5A:heme reduces Asc.- to AscH-"
Reactome:R-HSA-2855252 "AKRs reduce RBP2:atRAL to RBP2:atROL"
Reactome:R-HSA-5423637 "AKR dimers reduce AFBDHO to AFBDOH"
Reactome:R-HSA-5692232 "AKR1A1 oxidises BaPtDHD to BaP-7,8-dione"
Reactome:R-HSA-9027531 "Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA"
Reactome:R-HSA-9027562 "Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA"
Reactome:R-HSA-9027598 "Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3"
Reactome:R-HSA-9027600 "Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3"
Reactome:R-HSA-9937340 "DHRSX reduces dolichal to dolichol"
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