FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term 4-alpha-hydroxytetrahydrobiopterin dehydratase activity ID (Ontology) GO:0008124 (Gene Ontology)
Definition Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.[ EC:4 ]
Also Known As "4a-hydroxytetrahydrobiopterin dehydratase activity" ; "pterin-4-alpha-carbinolamine dehydratase activity" ; "pterin-4a-carbinolamine dehydratase activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | 4-alpha-hydroxytetrahydrobiopterin dehydratase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  carbon-oxygen lyase activity
   |__hydro-lyase activity
       |__4-alpha-hydroxytetrahydrobiopterin dehydratase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a hydro-lyase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]" RELATED
    "4-alpha-hydroxy-tetrahydropterin dehydratase activity" RELATED[ EC:4 ]
    "4a-hydroxytetrahydrobiopterin dehydratase activity" EXACT
    "4a-hydroxytetrahydrobiopterin hydro-lyase activity" RELATED[ EC:4 ]
    "4alpha-hydroxy-tetrahydropterin dehydratase activity" RELATED[ EC:4 ]
    "pterin-4-alpha-carbinolamine dehydratase activity" EXACT
    "pterin-4a-carbinolamine dehydratase activity" EXACT
    "pterin-4alpha-carbinolamine dehydratase activity" RELATED
    "tetrahydrobiopterin dehydratase activity" RELATED[ EC:4 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:4.2.1.96
KEGG_REACTION:R04734
MetaCyc:RXN-7908
Reactome:R-HSA-71146 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O"
RHEA:11920