FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein tyrosine/serine/threonine phosphatase activity ID (Ontology) GO:0008138 (Gene Ontology)
Definition Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein tyrosine/serine/threonine phosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein tyrosine/serine/threonine phosphatase activity       --
 NOT | enables | protein tyrosine/serine/threonine phosphatase activity       --
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phosphatase activity_____________________
catalytic activity, acting on a protein__|
                                         phosphoprotein phosphatase activity
                                          |__protein tyrosine/serine/threonine phosphatase activity  14 rec.
                                              |__JUN kinase phosphatase activity 2 rec.
                                              |__MAP kinase tyrosine/serine/threonine phosphatase activity 3 rec.
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Is a phosphoprotein phosphatase activity
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Synonyms
  • "dual-specificity protein phosphatase" BROAD
Secondary IDs
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Reactome:R-HSA-5675373 "Nuclear DUSPs dephosphorylate MAPKs"
Reactome:R-HSA-5675376 "Cytosolic DUSPs dephosphorylate MAPKs"
Reactome:R-HSA-9652816 "Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs"