FB2026_03 , released September 17, 2026
CV Term Report
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Term O-methyltransferase activity ID (Ontology) GO:0008171 (Gene Ontology)
Definition Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 O-methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | O-methyltransferase activity
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  transferase activity, transferring one-carbon groups
   |__methyltransferase activity
       |__O-methyltransferase activity  15 rec.
           |__(iso)eugenol O-methyltransferase activity
           |__2-phytyl-1,4-naphthoquinone methyltransferase activity
           |__2-polyprenyl-6-hydroxyphenol O-methyltransferase activity
           |__3-demethylubiquinol 3-O-methyltransferase activity 1 rec.
           |__3-demethylubiquinone 3-O-methyltransferase activity
           |__4-vinylphenol methyltransferase activity
           |__acetylserotonin O-methyltransferase activity
           |__caffeate O-methyltransferase activity
           |__caffeoyl-CoA O-methyltransferase activity
           |__carboxyl-O-methyltransferase activity 4 rec.
           |   |__gibberellin carboxyl-O-methyltransferase activity
           |   |__protein carboxyl O-methyltransferase activity(+) 4 rec.
           |__catechol O-methyltransferase activity
           |__demethylsterigmatocystin 6-O-methyltransferase activity
           |__farnesoic acid O-methyltransferase activity 1 rec.
           |__flavone 3'-O-methyltransferase activity
           |__isoflavone 7-O-methyltransferase activity
           |__isoliquiritigenin 2'-O-methyltransferase activity
           |__kaempferol 4'-O-methyltransferase activity
           |__laricitrin 5'-O-methyltransferase activity
           |__magnesium protoporphyrin IX methyltransferase activity
           |__methyltransferase cap1 activity 2 rec.
           |__methyltransferase cap2 activity 1 rec.
           |__myricetin 3'-O-methyltransferase activity
           |__RNA 2'-O-methyltransferase activity 4 rec.
           |   |__23S rRNA (adenosine(1067)-2'-O-ribose)-methyltransferase activity
           |   |__rRNA (cytosine-2'-O-ribose)-methyltransferase activity
           |   |__rRNA (guanosine-2'-O-ribose)-methyltransferase activity 1 rec.
           |   |__rRNA (uridine-2'-O-ribose)-methyltransferase activity 3 rec.
           |   |__small RNA 2'-O-ribose methyltransferase activity(+) 1 rec.
           |__RNA 5'-gamma-phosphate methyltransferase activity
           |__S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity
           |__sterigmatocystin 7-O-methyltransferase activity
           |__tocopherol C-methyltransferase activity
           |__tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity
           |__trihydroxyferuloyl spermidine O-methyltransferase activity
           |__trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity
           |__vitexin 2''-O-rhamnoside 7-O-methyltransferase activity
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Reactome:R-HSA-5578717 "BCDIN3D dimethylates 5' phosphate of pre-miR-145"
Reactome:R-HSA-5629203 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH"
Reactome:R-HSA-5629218 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1"
Reactome:R-HSA-5629237 "HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH"
Reactome:R-HSA-6790907 "Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides"