FB2026_03 , released September 17, 2026
CV Term Report
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Term RNA methyltransferase activity ID (Ontology) GO:0008173 (Gene Ontology)
Definition Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 RNA methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | RNA methyltransferase activity       --
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transferase activity, transferring one-carbon groups
 |__methyltransferase activity________________
catalytic activity, acting on a nucleic acid  |
 |__catalytic activity, acting on RNA_________|
                                              RNA methyltransferase activity  57 rec.
                                               |__methyltransferase cap1 activity 2 rec.
                                               |__methyltransferase cap2 activity 1 rec.
                                               |__mRNA methyltransferase activity 6 rec.
                                               |   |__internal mRNA (guanine-N7-)-methyltransferase activity
                                               |   |__mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
                                               |   |__mRNA (adenine-N1-)-methyltransferase activity
                                               |   |__mRNA (cytidine-5-)-methyltransferase activity 1 rec.
                                               |   |__mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1 rec.
                                               |   |__mRNA m(6)A methyltransferase activity 3 rec.
                                               |__RNA 2'-O-methyltransferase activity 4 rec.
                                               |   |__23S rRNA (adenosine(1067)-2'-O-ribose)-methyltransferase activity
                                               |   |__rRNA (cytosine-2'-O-ribose)-methyltransferase activity
                                               |   |__rRNA (guanosine-2'-O-ribose)-methyltransferase activity 1 rec.
                                               |   |__rRNA (uridine-2'-O-ribose)-methyltransferase activity 3 rec.
                                               |   |__small RNA 2'-O-ribose methyltransferase activity(+) 1 rec.
                                               |__RNA 5'-gamma-phosphate methyltransferase activity
                                               |__RNA cap trimethylguanosine synthase activity 1 rec.
                                               |__rRNA methyltransferase activity 21 rec.
                                               |   |__rRNA (adenine) methyltransferase activity(+) 6 rec.
                                               |   |__rRNA (cytosine) methyltransferase activity(+) 6 rec.
                                               |   |__rRNA (guanine) methyltransferase activity(+) 3 rec.
                                               |   |__rRNA (pseudouridine) methyltransferase activity(+) 1 rec.
                                               |   |__rRNA (uridine) methyltransferase activity(+) 4 rec.
                                               |__snRNA methyltransferase activity 2 rec.
                                               |   |__U2 snRNA (2'-O-methyladenosine-N6)-methyltransferase activity
                                               |   |__U2 snRNA (adenine-N6)-methyltransferase activity 1 rec.
                                               |   |__U6 snRNA (adenine(43)-N6)-methyltransferase activity 1 rec.
                                               |   |__U6 snRNA (guanine-N(2))-methyltransferase activity
                                               |__tRNA methyltransferase activity 23 rec.
                                                   |__tRNA (adenine) methyltransferase activity(+) 4 rec.
                                                   |__tRNA (cytidine) methyltransferase activity(+) 7 rec.
                                                   |__tRNA (guanine) methyltransferase activity(+) 10 rec.
                                                   |__tRNA (uridine) methyltransferase activity(+) 4 rec.
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Is a methyltransferase activity
catalytic activity, acting on RNA
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Reactome:R-HSA-191784 "snRNA Cap hypermethylation"