FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term tRNA methyltransferase activity ID (Ontology) GO:0008175 (Gene Ontology)
Definition Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       5
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 tRNA methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1      5
     enables | tRNA methyltransferase activity       --       5
Spanning Tree (Parents/Children)
Only view relationship: 
methyltransferase activity
 |__RNA methyltransferase activity________
catalytic activity, acting on RNA         |
 |__RNA methyltransferase activity________|
 |__catalytic activity, acting on a tRNA__|
                                          tRNA methyltransferase activity  24 rec.
                                           |__tRNA (adenine) methyltransferase activity 4 rec.
                                           |   |__tRNA (adenine(9)-N1)-methyltransferase activity 1 rec.
                                           |   |__tRNA (adenine(22)-N1)-methyltransferase activity
                                           |   |__tRNA (adenine(37)-C2)-methyltransferase activity
                                           |   |__tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
                                           |   |__tRNA (adenine(58)-N1)-methyltransferase activity 1 rec.
                                           |   |__tRNA (adenine-N6)-methyltransferase activity
                                           |   |__tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity 2 rec.
                                           |__tRNA (cytidine) methyltransferase activity 7 rec.
                                           |   |__tRNA (cytidine(32)-2'-O)-methyltransferase activity 1 rec.
                                           |   |__tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase activity
                                           |   |__tRNA (cytidine(34)-2'-O)-methyltransferase activity 1 rec.
                                           |   |__tRNA (cytidine(56)-2'-O)-methyltransferase activity
                                           |   |__tRNA (cytidine-3-)-methyltransferase activity 1 rec.
                                           |   |__tRNA (cytidine-5-)-methyltransferase activity 3 rec.
                                           |__tRNA (guanine) methyltransferase activity 10 rec.
                                           |   |__tRNA (guanine(6)-N2)-methyltransferase activity
                                           |   |__tRNA (guanine(7)-N2)-methyltransferase activity
                                           |   |__tRNA (guanine(10)-N2)-dimethyltransferase activity
                                           |   |__tRNA (guanine(10)-N2)-methyltransferase activity 1 rec.
                                           |   |__tRNA (guanine(18)-2'-O)-methyltransferase activity 1 rec.
                                           |   |__tRNA (guanine(26)-N2)-dimethyltransferase activity 1 rec.
                                           |   |__tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity
                                           |   |__tRNA (guanine(27)-N2)-dimethyltransferase activity
                                           |   |__tRNA (guanine(37)-N1)-methyltransferase activity 1 rec.
                                           |   |__tRNA (guanine(46)-N7)-methyltransferase activity 2 rec.
                                           |   |__tRNA (guanosine(9)-N1)-methyltransferase activity 2 rec.
                                           |   |__tRNA (guanosine(34)-2'-O)-methyltransferase activity 2 rec.
                                           |__tRNA (uridine) methyltransferase activity 4 rec.
                                           |   |__tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity
                                           |   |__tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
                                           |   |__tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity 2 rec.
                                           |   |__tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity
                                           |   |__tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase activity
                                           |   |__tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent
                                           |   |__tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 1 rec.
                                           |   |__tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity 1 rec.
                                           |__tRNA 2'-O-methyltransferase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a RNA methyltransferase activity
catalytic activity, acting on a tRNA
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-6782879 "TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe)"
Reactome:R-HSA-6782881 "LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe)"
Reactome:R-HSA-6782890 "LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe)"
Reactome:R-HSA-6783473 "LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe)"
Reactome:R-HSA-6786500 "ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34"
Reactome:R-HSA-6786567 "KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine"