FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

COP9 signalosome

ID (Ontology)

GO:0008180 (Gene Ontology)

Definition

A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.[ PubMed:11019806 PubMed:12186635 PubMed:14570571 ]

Also Known As

"COP9 complex" ; "CSN"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
COP9 signalosome (all annotations which use CV term, excluding "NOT" statements)
part_of \| COP9 signalosome	--

Spanning Tree (Parents/Children)

nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__COP9 signalosome  14 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	nuclear protein-containing complex
Part of
Synonyms & Secondary IDs
Synonyms
	"COP9 complex" EXACT "CSN" EXACT "signalosome" BROAD
Secondary IDs

External Crossreferences & Linkouts