FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term omega peptidase activity ID (Ontology) GO:0008242 (Gene Ontology)
Definition Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.[ EC:3 PubMed:20157488 PubMed:9920379 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 omega peptidase activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | omega peptidase activity       2
Spanning Tree (Parents/Children)
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hydrolase activity_______________________
catalytic activity, acting on a protein__|
                                         peptidase activity
                                          |__omega peptidase activity  12 rec.
                                              |__beta-aspartyl-peptidase activity 2 rec.
                                              |__gamma-glutamyl-peptidase activity 3 rec.
                                              |__glutathione gamma-glutamate hydrolase 5 rec.
                                              |__leukotriene-C(4) hydrolase activity
                                              |__pyroglutamyl-peptidase activity 2 rec.
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Is a peptidase activity
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Synonyms
  • "peptidase activity, acting on peptides containing modified amino acids" RELATED
Secondary IDs
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EC:3.4.19.-
EC:3.4.19.1
EC:3.4.19.2
MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN
MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN
Reactome:R-HSA-5696365 "ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH"