FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term calcium, potassium:sodium antiporter activity ID (Ontology) GO:0008273 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       5
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 calcium, potassium:sodium antiporter activity (all annotations which use CV term, excluding "NOT" statements)       1      5
     enables | calcium, potassium:sodium antiporter activity       --       5
Spanning Tree (Parents/Children)
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potassium ion transmembrane transporter activity
 |__solute:potassium antiporter activity____________
sodium ion transmembrane transporter activity       |
 |__calcium:sodium antiporter activity______________|
calcium:monoatomic cation antiporter activity       |
 |__calcium:sodium antiporter activity______________|
metal cation:monoatomic cation antiporter activity  |
 |__solute:potassium antiporter activity____________|
                                                    calcium, potassium:sodium antiporter activity  6 rec.
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Is a calcium:sodium antiporter activity
solute:potassium antiporter activity
Part of
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Synonyms
  • "potassium-dependent sodium/calcium exchanger" RELATED
Secondary IDs
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Reactome:R-HSA-2514891 "SLC24A1 exchanges 4Na+ for Ca2+, K+"
Reactome:R-HSA-425678 "SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+"
Reactome:R-HSA-5625841 "Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+"
Reactome:R-HSA-5626270 "Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+"
Reactome:R-HSA-5626316 "SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+"
Reactome:R-HSA-5626356 "Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+"
RHEA:69967