FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term gamma-butyrobetaine dioxygenase activity ID (Ontology) GO:0008336 (Gene Ontology)
Definition Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O2 = carnitine + CO2 + succinate.[ EC:1 ]
Also Known As "g-butyrobetaine dioxygenase activity" ; "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity"
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 gamma-butyrobetaine dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | gamma-butyrobetaine dioxygenase activity       --       3
Spanning Tree (Parents/Children)
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oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__
dioxygenase activity___________________________________________________________________________________|
                                                                                         2-oxoglutarate-dependent dioxygenase activity
                                                                                          |__gamma-butyrobetaine dioxygenase activity  4 rec.
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Is a 2-oxoglutarate-dependent dioxygenase activity
Part of
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Synonyms
  • "4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" RELATED[ EC:1 ]
    "alpha-butyrobetaine hydroxylase activity" RELATED[ EC:1 ]
    "butyrobetaine hydroxylase activity" RELATED[ EC:1 ]
    "g-butyrobetaine dioxygenase activity" EXACT
    "gamma-BBH activity" RELATED[ EC:1 ]
    "gamma-butyrobetaine hydroxylase activity" RELATED[ EC:1 ]
    "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity" EXACT
Secondary IDs
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EC:1.14.11.1
KEGG_REACTION:R02397
MetaCyc:1.14.11.1-RXN
Reactome:R-HSA-71261 "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA"
RHEA:24028