FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term RNA polymerase II CTD heptapeptide repeat kinase activity ID (Ontology) GO:0008353 (Gene Ontology)
Definition Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.[ EC:2 PubMed:28248323 ]
Also Known As "RNA polymerase II carboxy-terminal domain kinase activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 RNA polymerase II CTD heptapeptide repeat kinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | RNA polymerase II CTD heptapeptide repeat kinase activity       --
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
protein kinase activity
 |__protein serine/threonine kinase activity______________________
catalytic activity, acting on a protein                           |
 |__RNA polymerase II CTD heptapeptide repeat modifying activity__|
                                                                  RNA polymerase II CTD heptapeptide repeat kinase activity  5 rec.
                                                                   |__RNA polymerase II CTD heptapeptide repeat S2 kinase activity
                                                                   |__RNA polymerase II CTD heptapeptide repeat S5 kinase activity
                                                                   |__RNA polymerase II CTD heptapeptide repeat S7 kinase activity
                                                                   |__RNA polymerase II CTD heptapeptide repeat T4 kinase activity
                                                                   |__RNA polymerase II CTD heptapeptide repeat Y1 kinase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a protein serine/threonine kinase activity
RNA polymerase II CTD heptapeptide repeat modifying activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "[RNA-polymerase]-subunit kinase activity" BROAD
    "CTD kinase activity" RELATED[ EC:2 ]
    "RNA polymerase II carboxy-terminal domain kinase activity" EXACT
    "RNA polymerase subunit kinase activity" BROAD[ EC:2 ]
    "RNA-polymerase-subunit kinase activity" BROAD[ EC:2 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:2.7.11.23
MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN
Reactome:R-HSA-167191 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex"
Reactome:R-HSA-170704 "Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex"
Reactome:R-HSA-170706 "Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex"
RHEA:10216