FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term sialyltransferase activity ID (Ontology) GO:0008373 (Gene Ontology)
Definition Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.[ PubMed:26192491 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 sialyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1      1
     enables | sialyltransferase activity       --       1
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  transferase activity
   |__glycosyltransferase activity
       |__sialyltransferase activity  2 rec.
           |__alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
           |__alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
           |__alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity
           |__beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase activity
           |__beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
           |__beta-galactoside alpha-2,3-sialyltransferase activity
           |__beta-galactoside alpha-2,6-sialyltransferase activity 1 rec.
           |__galactosyldiacylglycerol alpha-2,3-sialyltransferase activity
           |__lactosylceramide alpha-2,3-sialyltransferase activity
           |__N-acetyllactosaminide alpha-2,3-sialyltransferase activity
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Is a glycosyltransferase activity
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EC:2.4.3.-
Reactome:R-HSA-9683769 "O-glycosylation of 3a is terminated"
Reactome:R-HSA-9694718 "O-glycosylation of 3a is terminated"
Reactome:R-HSA-9697018 "Addition of sialic acids on some Spike glycosyl sidechains"
Reactome:R-HSA-981814 "ST6GALNAC2 transfers sialic acid to Core 1 mucins"
Wikipedia:Sialyltransferase