FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term 5'-3' exonuclease activity ID (Ontology) GO:0008409 (Gene Ontology)
Definition Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       5
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 5'-3' exonuclease activity (all annotations which use CV term, excluding "NOT" statements)       5
     enables | 5'-3' exonuclease activity       5
Spanning Tree (Parents/Children)
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nuclease activity__________________________
hydrolase activity, acting on ester bonds__|
                                           exonuclease activity
                                            |__5'-3' exonuclease activity  13 rec.
                                                |__5'-3' DNA exonuclease activity 6 rec.
                                                |   |__double-stranded DNA 5'-3' DNA exonuclease activity 1 rec.
                                                |   |__single-stranded DNA 5'-3' DNA exonuclease activity 1 rec.
                                                |__5'-3' RNA exonuclease activity 5 rec.
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Reactome:R-HSA-5358599 "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch"
Reactome:R-HSA-5358619 "EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL)"