FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term glycoprotein 6-alpha-L-fucosyltransferase activity ID (Ontology) GO:0008424 (Gene Ontology)
Definition Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 glycoprotein 6-alpha-L-fucosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | glycoprotein 6-alpha-L-fucosyltransferase activity
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fucosyltransferase activity
 |__alpha-(1->6)-fucosyltransferase activity______
catalytic activity, acting on a protein           |
 |__catalytic activity, acting on a glycoprotein__|
                                                  glycoprotein 6-alpha-L-fucosyltransferase activity  1 rec.
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Is a alpha-(1->6)-fucosyltransferase activity
catalytic activity, acting on a glycoprotein
Part of
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Synonyms
  • "FucT" RELATED[ EC:2 ]
    "GDP-fucose--glycoprotein fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-fucose--glycoprotein fucosyltransferase activity" RELATED[ EC:2 ]
    "GDPfucose-glycoprotein fucosyltransferase activity" RELATED[ EC:2 ]
    "glycoprotein fucosyltransferase activity" BROAD[ EC:2 ]
    "guanosine diphosphofucose--glycoprotein fucosyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.68
KEGG_REACTION:R05988
MetaCyc:2.4.1.68-RXN
Reactome:R-HSA-1028788 "FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP"
Reactome:R-HSA-9696980 "Spike trimer glycoside chains get additional branches"
RHEA:12985