FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity ID (Ontology) GO:0008454 (Gene Ontology)
Definition Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.[ EC:2 ]
Also Known As"alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
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UDP-glycosyltransferase activity
 |__acetylglucosaminyltransferase activity________
hexosyltransferase activity                       |
 |__acetylglucosaminyltransferase activity________|
catalytic activity, acting on a protein           |
 |__catalytic activity, acting on a glycoprotein__|
                                                  alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity  2 rec.
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Is a acetylglucosaminyltransferase activity
catalytic activity, acting on a glycoprotein
Part of
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Synonyms
  • "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT
    "beta-acetylglucosaminyltransferase IV activity" RELATED[ EC:2 ]
    "GnTIV activity" RELATED[ EC:2 ]
    "N-acetylglucosaminyltransferase IV activity" RELATED[ EC:2 ]
    "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity" RELATED[ EC:2 ]
    "UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" RELATED
    "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.145
MetaCyc:2.4.1.145-RXN
Reactome:R-HSA-9696980 "Spike trimer glycoside chains get additional branches"
Reactome:R-HSA-975903 "Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV"
RHEA:16057