FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity ID (Ontology) GO:0008455 (Gene Ontology)
Definition Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.[ EC:2 ]
Also Known As "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
UDP-glycosyltransferase activity
 |__acetylglucosaminyltransferase activity________
hexosyltransferase activity                       |
 |__acetylglucosaminyltransferase activity________|
catalytic activity, acting on a protein           |
 |__catalytic activity, acting on a glycoprotein__|
                                                  alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity  1 rec.
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Is a acetylglucosaminyltransferase activity
catalytic activity, acting on a glycoprotein
Part of
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Synonyms
  • "acetylglucosaminyltransferase II activity" RELATED[ EC:2 ]
    "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT
    "GnTII activity" RELATED[ EC:2 ]
    "N-acetylglucosaminyltransferase II activity" RELATED[ EC:2 ]
    "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity" RELATED[ EC:2 ]
    "UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.143
MetaCyc:2.4.1.143-RXN
Reactome:R-HSA-4793955 "Defective MGAT2 does not transfer GlcNAc to N-glycans"
Reactome:R-HSA-9694656 "Spike trimer glycoside chains are extended"
Reactome:R-HSA-975829 "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2"
RHEA:12941