FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term [heparan sulfate]-glucosamine 3-sulfotransferase activity ID (Ontology) GO:0008467 (Gene Ontology)
Definition Catalysis of the reaction: alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H+.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 [heparan sulfate]-glucosamine 3-sulfotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | [heparan sulfate]-glucosamine 3-sulfotransferase activity
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  proteoglycan sulfotransferase activity
   |__heparan sulfate sulfotransferase activity
       |__[heparan sulfate]-glucosamine 3-sulfotransferase activity  2 rec.
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Is a heparan sulfate sulfotransferase activity
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Synonyms
  • "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase" BROAD
    "3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity" RELATED
    "3-OST activity" RELATED
    "[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity" NARROW
    "[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity" NARROW
    "[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity" NARROW
    "glucosaminyl 3-O-sulfotransferase activity" RELATED
    "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" RELATED
    "heparin-glucosamine 3-O-sulfotransferase activity" RELATED
    "heparin-glucosamine 3-O-sulphotransferase activity" RELATED
Secondary IDs
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EC:2.8.2.23
EC:2.8.2.29
EC:2.8.2.30
MetaCyc:2.8.2.23-RXN
MetaCyc:2.8.2.29-RXN
MetaCyc:2.8.2.30-RXN
Reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate"
Reactome:R-HSA-2076611 "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate"
RHEA:15461