FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term 3-methylbutanoyl-CoA dehydrogenase activity ID (Ontology) GO:0008470 (Gene Ontology)
Definition Catalysis of the reaction: 3-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein].[ PubMed:25450250 PubMed:7640268 ]
Also Known As "isovaleryl-CoA dehydrogenase activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 3-methylbutanoyl-CoA dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | 3-methylbutanoyl-CoA dehydrogenase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  acyl-CoA dehydrogenase activity
   |__short-chain fatty acyl-CoA dehydrogenase activity
       |__3-methylbutanoyl-CoA dehydrogenase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a short-chain fatty acyl-CoA dehydrogenase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity" RELATED[ EC:1 ]
    "3-methylbutanoyl-CoA:acceptor oxidoreductase activity" RELATED[ EC:1 ]
    "isovaleroyl-coenzyme A dehydrogenase activity" RELATED[ EC:1 ]
    "isovaleryl-CoA dehydrogenase activity" EXACT
    "isovaleryl-coenzyme A dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:1.3.8.4
MetaCyc:RXN0-2301
Reactome:R-HSA-70745 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2"
Reactome:R-HSA-9914837 "IVD mutants don't synthesize beta-methylcrotonyl-CoA"
RHEA:12276