FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein-tyrosine sulfotransferase activity ID (Ontology) GO:0008476 (Gene Ontology)
Definition Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.[ EC:2 ]
Also Known As"protein-tyrosine sulphotransferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein-tyrosine sulfotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein-tyrosine sulfotransferase activity
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catalytic activity
 |__catalytic activity, acting on a protein___________________
transferase activity, transferring sulphur-containing groups  |
 |__sulfotransferase activity_________________________________|
                                                              protein-tyrosine sulfotransferase activity  1 rec.
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Is a sulfotransferase activity
catalytic activity, acting on a protein
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Synonyms
  • "3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity" RELATED[ EC:2 ]
    "protein-tyrosine sulphotransferase activity" EXACT
    "tyrosylprotein sulfotransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.8.2.20
MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN
Reactome:R-HSA-8954262 "TPST1,2 transfer SO4 (2-) from PAPS to PODXL2"
Reactome:R-HSA-9668023 "TPST1,2 transfer SO4 (2-) from PAPS to FVIII"
Reactome:R-HSA-9668148 "F8 variant is not sulfonated at Y1699"
RHEA:16801