FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term sphingosine kinase activity ID (Ontology) GO:0008481 (Gene Ontology)
Definition Catalysis of the reaction: a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H+.
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 sphingosine kinase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | sphingosine kinase activity       --       2
Spanning Tree (Parents/Children)
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kinase activity
 |__lipid kinase activity________________________________________
transferase activity, transferring phosphorus-containing groups  |
 |__phosphotransferase activity, alcohol group as acceptor_______|
                                                                 sphingosine kinase activity  3 rec.
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Is a lipid kinase activity
phosphotransferase activity, alcohol group as acceptor
Part of
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Synonyms
  • "ATP:sphinganine 1-phosphotransferase activity" RELATED[ EC:2 ]
    "dihydrosphingosine kinase (phosphorylating)" RELATED[ EC:2 ]
    "dihydrosphingosine kinase activity" RELATED[ EC:2 ]
    "sphinganine kinase activity" RELATED
    "sphingosine kinase (phosphorylating)" RELATED[ EC:2 ]
Secondary IDs
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EC:2.7.1.91
MetaCyc:SPHINGANINE-KINASE-RXN
Reactome:R-HSA-5218845 "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate"
Reactome:R-HSA-9625814 "SPHK1 phosphorylates sphingosine in response to E2 stimulation"
RHEA:15465
RHEA:33563
RHEA:34715
RHEA:34747
RHEA:35847
RHEA:51496
RHEA:63956