FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sodium:bicarbonate symporter activity ID (Ontology) GO:0008510 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
Also Known As"sodium:hydrogencarbonate symporter activity"
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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 sodium:bicarbonate symporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sodium:bicarbonate symporter activity
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sodium ion transmembrane transporter activity
 |__solute:sodium symporter activity__________________
bicarbonate transmembrane transporter activity        |
 |__monoatomic cation:bicarbonate symporter activity__|
solute:monoatomic cation symporter activity           |
 |__solute:sodium symporter activity__________________|
 |__monoatomic cation:bicarbonate symporter activity__|
                                                      sodium:bicarbonate symporter activity  1 rec.
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Is a solute:sodium symporter activity
monoatomic cation:bicarbonate symporter activity
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Synonyms
  • "sodium/bicarbonate cotransporter activity" BROAD
    "sodium:bicarbonate cotransporter activity" BROAD
    "sodium:hydrogencarbonate symporter activity" EXACT
Secondary IDs
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Reactome:R-HSA-425483 "SLC4A5,7,9 cotransport Na+ with 3HCO3-"
Reactome:R-HSA-5656219 "Defective SLC4A4 does not cotransport Na+ with 3HCO3-"
Reactome:R-HSA-8878664 "SLC4A4 cotransports Na+ with 3HCO3-"
RHEA:70267