FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term sodium:potassium:chloride symporter activity ID (Ontology) GO:0008511 (Gene Ontology)
Definition Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).
Also Known As "sodium/potassium/chloride symporter activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 sodium:potassium:chloride symporter activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | sodium:potassium:chloride symporter activity       --       2
Spanning Tree (Parents/Children)
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potassium ion transmembrane transporter activity
 |__potassium:sodium symporter activity________
 |__potassium:chloride symporter activity______|
solute:sodium symporter activity               |
 |__potassium:sodium symporter activity________|
monoatomic anion:sodium symporter activity     |
 |__sodium:chloride symporter activity_________|
chloride:monoatomic cation symporter activity  |
 |__sodium:chloride symporter activity_________|
 |__potassium:chloride symporter activity______|
                                               sodium:potassium:chloride symporter activity  3 rec.
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Is a potassium:sodium symporter activity
sodium:chloride symporter activity
potassium:chloride symporter activity
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Synonyms
  • "sodium/potassium/chloride symporter activity" EXACT
Secondary IDs
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Reactome:R-HSA-426086 "SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol"
Reactome:R-HSA-5623588 "Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol"
RHEA:72395