FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ABC-type xenobiotic transporter activity ID (Ontology) GO:0008559 (Gene Ontology)
Definition Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).[ EC:7 ]
Also Known As"ATP-dependent xenobiotic transmembrane transporter activity" ; "xenobiotic transmembrane transporting ATPase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ABC-type xenobiotic transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | ABC-type xenobiotic transporter activity
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transmembrane transporter activity
 |__xenobiotic transmembrane transporter activity__
ATPase-coupled transmembrane transporter activity  |
 |__ABC-type transporter activity__________________|
                                                   ABC-type xenobiotic transporter activity  5 rec.
                                                    |__ABC-type bacteriocin transporter activity
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Is a xenobiotic transmembrane transporter activity
ABC-type transporter activity
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Synonyms
  • "ATP phosphohydrolase (xenobiotic-exporting)" RELATED[ EC:7 ]
    "ATP-dependent xenobiotic transmembrane transporter activity" EXACT
    "ATPase-coupled xenobiotic transmembrane transporter activity" RELATED
    "MDR protein" RELATED[ EC:7 ]
    "multidrug resistance exporter" RELATED
    "multidrug-resistance protein" RELATED
    "P-glycoprotein" RELATED[ EC:7 ]
    "PDR protein" RELATED[ EC:7 ]
    "pleiotropic-drug-resistance protein" RELATED[ EC:7 ]
    "xenobiotic ABC transporter" NARROW
    "xenobiotic transmembrane transporting ATPase activity" EXACT
Secondary IDs
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EC:7.6.2.2
MetaCyc:3.6.3.44-RXN
Reactome:R-HSA-9757139 "ABCB1,ABCC2 transport ATVs from cytosol to extracellular region"
Reactome:R-HSA-9911514 "MacA:MacB:TolC transports azithromycin from the cytosol to the periplasm"
RHEA:33147