FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term peptidyl-hypusine biosynthetic process ID (Ontology) GO:0008612 (Gene Ontology)
Definition The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine, an unusual amino acid synthesized post-translationally.[ PubMed:19880510 PubMed:22438895 ]
Also Known As "hypusine anabolism" ; "hypusine anabolism from peptidyl-lysine" ; "hypusine biosynthesis" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 peptidyl-hypusine biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | peptidyl-hypusine biosynthetic process       --
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metabolic process
 |__biosynthetic process___
gene expression            |
 |__protein maturation_____|
protein metabolic process  |
 |__protein maturation_____|
                           peptidyl-hypusine biosynthetic process  3 rec.
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Is a biosynthetic process
protein maturation
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Synonyms
  • "hypusine anabolism" EXACT
    "hypusine anabolism from peptidyl-lysine" EXACT
    "hypusine biosynthesis" EXACT
    "hypusine biosynthetic process" EXACT
    "hypusine biosynthetic process from peptidyl-lysine" EXACT
    "hypusine formation" EXACT
    "hypusine formation from peptidyl-lysine" EXACT
    "hypusine synthesis" EXACT
    "hypusine synthesis from peptidyl-lysine" EXACT
    "hypusinylation" EXACT
    "protein hypusination" EXACT
Secondary IDs
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MetaCyc:PWY-5905
Reactome:R-HSA-204626 "Hypusine synthesis from eIF5A-lysine"