FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

epsilon DNA polymerase complex

ID (Ontology)

GO:0008622 (Gene Ontology)

Definition

A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.[ PubMed:15814431 PubMed:9745046 ]

Also Known As

"DNA polymerase epsilon complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
epsilon DNA polymerase complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| epsilon DNA polymerase complex	--

Spanning Tree (Parents/Children)

nucleus
 |__nuclear protein-containing complex__________________________
chromosome                                                      |
 |__nuclear chromosome__________________________________________|
nuclear lumen                                                   |
 |__nuclear chromosome__________________________________________|
protein-containing complex                                      |
 |__nuclear protein-containing complex__________________________|
transferase complex, transferring phosphorus-containing groups  |
 |__DNA polymerase complex______________________________________|
intracellular protein-containing complex                        |
 |__DNA polymerase complex______________________________________|
                                                                epsilon DNA polymerase complex  5 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	DNA polymerase complex nuclear protein-containing complex
Part of	nuclear chromosome
Synonyms & Secondary IDs
Synonyms
	"DNA polymerase epsilon complex" EXACT
Secondary IDs

External Crossreferences & Linkouts