FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term rRNA methyltransferase activity ID (Ontology) GO:0008649 (Gene Ontology)
Definition Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. The methyl group can be transfered to the nucleobase or to the ribose group of the nucleoside.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 rRNA methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | rRNA methyltransferase activity       --
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methyltransferase activity
 |__RNA methyltransferase activity_____________________________
 |__S-adenosylmethionine-dependent methyltransferase activity__|
catalytic activity, acting on RNA                              |
 |__RNA methyltransferase activity_____________________________|
 |__catalytic activity, acting on a rRNA_______________________|
                                                               rRNA methyltransferase activity  21 rec.
                                                                |__rRNA (adenine) methyltransferase activity 6 rec.
                                                                |   |__23S rRNA (adenosine(1067)-2'-O-ribose)-methyltransferase activity
                                                                |   |__rRNA (adenine(2503)-C2-)-methyltransferase activity
                                                                |   |__rRNA (adenine-N1-)-methyltransferase activity 1 rec.
                                                                |   |__rRNA (adenine-N6,N6-)-dimethyltransferase activity(+) 3 rec.
                                                                |   |__rRNA (adenine-N6-)-methyltransferase activity(+) 2 rec.
                                                                |__rRNA (cytosine) methyltransferase activity 6 rec.
                                                                |   |__rRNA (cytosine-2'-O-ribose)-methyltransferase activity
                                                                |   |__rRNA (cytosine-C5-)-methyltransferase activity 5 rec.
                                                                |   |__rRNA (cytosine-N4-)-methyltransferase activity 1 rec.
                                                                |__rRNA (guanine) methyltransferase activity 3 rec.
                                                                |   |__rRNA (guanine-N1-)-methyltransferase activity(+)
                                                                |   |__rRNA (guanine-N2-)-methyltransferase activity(+)
                                                                |   |__rRNA (guanine-N7-)-methyltransferase activity
                                                                |   |__rRNA (guanosine-2'-O-ribose)-methyltransferase activity 1 rec.
                                                                |__rRNA (pseudouridine) methyltransferase activity 1 rec.
                                                                |   |__rRNA (pseudouridine-N3-)-methyltransferase activity
                                                                |__rRNA (uridine) methyltransferase activity 4 rec.
                                                                    |__rRNA (uridine-2'-O-ribose)-methyltransferase activity 3 rec.
                                                                    |__rRNA (uridine-C5-)-methyltransferase activity
                                                                    |__rRNA (uridine-N3-)-methyltransferase activity 1 rec.
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Is a RNA methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
catalytic activity, acting on a rRNA
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Reactome:R-HSA-9911509 "RMTases methylate 16S ribosomal RNA"