FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term S-adenosylmethionine-dependent methyltransferase activity ID (Ontology) GO:0008757 (Gene Ontology)
Definition Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
Also Known As "S-adenosyl methionine-dependent methyltransferase activity" ; "SAM-dependent methyltransferase activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      10
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 S-adenosylmethionine-dependent methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)      10
     enables | S-adenosylmethionine-dependent methyltransferase activity      10
Spanning Tree (Parents/Children)
Only view relationship: 
  transferase activity, transferring one-carbon groups
   |__methyltransferase activity
       |__S-adenosylmethionine-dependent methyltransferase activity  127 rec.
           |__(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity
           |__(RS)-norcoclaurine 6-O-methyltransferase activity
           |__(S)-coclaurine-N-methyltransferase activity
           |__(S)-scoulerine 9-O-methyltransferase activity
           |__(S)-tetrahydroprotoberberine N-methyltransferase activity
           |__2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity
           |__2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity
           |__3'-demethylstaurosporine O-methyltransferase activity
           |__3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity
           |__3,5-dichloro-THPH methyl transferase activity
           |__3,7-dimethylquercitin 4'-O-methyltransferase activity
           |__3-demethylubiquinol 3-O-methyltransferase activity 1 rec.
           |__3-demethylubiquinone 3-O-methyltransferase activity
           |__3-hydroxyanthranilate 4-C-methyltransferase activity
           |__3-methylquercitin 7-O-methyltransferase activity
           |__4-vinylphenol methyltransferase activity
           |__5-hydroxyfuranocoumarin 5-O-methyltransferase activity
           |__6-hydroxymellein O-methyltransferase activity
           |__6-O-methylnorlaudanosoline 5'-O-methyltransferase activity
           |__8-hydroxyfuranocoumarin 8-O-methyltransferase activity
           |__8-hydroxyquercitin 8-O-methyltransferase activity
           |__10-hydroxydihydrosanguinarine 10-O-methyltransferase activity
           |__11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity
           |__12-hydroxydihydrochelirubine 12-O-methyltransferase activity
           |__16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity
           |__24-methylenesterol C-methyltransferase activity
           |__[cytochrome c]-methionine S-methyltransferase activity
           |__[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity
           |__acetylserotonin O-methyltransferase activity
           |__amine N-methyltransferase activity
           |__anthranilate N-methyltransferase activity
           |__apigenin 4'-O-methyltransferase activity
           |__arginine N-methyltransferase activity 13 rec.
           |   |__protein-arginine N-methyltransferase activity(+) 13 rec.
           |__arsenite methyltransferase activity
           |__caffeoyl-CoA O-methyltransferase activity
           |__carnosine N-methyltransferase activity 1 rec.
           |__catechol O-methyltransferase activity
           |__chlorophenol O-methyltransferase activity
           |__columbamine O-methyltransferase activity
           |__cycloartenol 24-C-methyltransferase activity
           |__cyclopropane-fatty-acyl-phospholipid synthase activity
           |__demethylmacrocin O-methyltransferase activity
           |__dimethylglycine N-methyltransferase activity
           |__diphthine methyl ester synthase activity 1 rec.
           |__diphthine synthase activity 1 rec.
           |__DNA (cytosine-5-)-methyltransferase activity 1 rec.
           |   |__ATP-dependent DNA (cytosine-5-)-methyltransferase activity
           |   |__DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
           |   |__DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates
           |   |__DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates
           |__farnesoic acid O-methyltransferase activity 1 rec.
           |__fatty acid O-methyltransferase activity
           |__flavone 3'-O-methyltransferase activity
           |__glucuronoxylan 4-O-methyltransferase activity
           |__glycine N-methyltransferase activity 1 rec.
           |__guanidinoacetate N-methyltransferase activity
           |__histamine N-methyltransferase activity
           |__indolepyruvate C-methyltransferase activity
           |__inositol 1-methyltransferase activity
           |__inositol 3-methyltransferase activity
           |__inositol 4-methyltransferase activity
           |__iodophenol O-methyltransferase activity
           |__isobutyraldoxime O-methyltransferase activity
           |__isoflavone 4'-O-methyltransferase activity
           |__isoflavone 7-O-methyltransferase activity
           |__isoliquiritigenin 2'-O-methyltransferase activity
           |__isoorientin 3'-O-methyltransferase activity
           |__kaempferol 4'-O-methyltransferase activity
           |__L-histidine N(alpha)-methyltransferase activity
           |__laricitrin 5'-O-methyltransferase activity
           |__licodione 2'-O-methyltransferase activity
           |__lipid A phosphate methyltransferase activity
           |__loganate O-methyltransferase activity
           |__lysine N-methyltransferase activity 52 rec.
           |   |__protein-lysine N-methyltransferase activity(+) 52 rec.
           |__macrocin O-methyltransferase activity
           |__magnesium protoporphyrin IX methyltransferase activity
           |__methionine S-methyltransferase activity
           |__methyl jasmonate methylesterase activity
           |__methylene-fatty-acyl-phospholipid synthase activity
           |__methylquercetagetin 6-O-methyltransferase activity
           |__mRNA methyltransferase activity 5 rec.
           |   |__internal mRNA (guanine-N7-)-methyltransferase activity
           |   |__mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
           |   |__mRNA (adenine-N1-)-methyltransferase activity
           |   |__mRNA (cytidine-5-)-methyltransferase activity
           |   |__mRNA 5'-cap (guanine-N7-)-methyltransferase activity 1 rec.
           |   |__mRNA m(6)A methyltransferase activity 3 rec.
           |__myricetin 3'-O-methyltransferase activity
           |__N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity
           |__N-terminal protein N-methyltransferase activity 1 rec.
           |__nicotinamide N-methyltransferase activity
           |__nicotinate N-methyltransferase activity
           |__O-demethylpuromycin O-methyltransferase activity
           |__phenol O-methyltransferase activity
           |__phenylethanolamine N-methyltransferase activity
           |__phosphatidyl-N-methylethanolamine N-methyltransferase activity
           |__phosphatidylethanolamine N-methyltransferase activity
           |__phosphoethanolamine N-methyltransferase activity
           |__polyprenyldihydroxybenzoate methyltransferase activity 1 rec.
           |__polysaccharide O-methyltransferase activity
           |__precorrin-2 C20-methyltransferase activity
           |__precorrin-3B C17-methyltransferase activity
           |__precorrin-4 C11-methyltransferase activity
           |__precorrin-6Y C5,15-methyltransferase (decarboxylating) activity
           |__protein C-terminal leucine carboxyl O-methyltransferase activity 1 rec.
           |__protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 1 rec.
           |__protein-arginine C-methyltransferase activity
           |__protein-cysteine methyltransferase activity 1 rec.
           |__protein-glutamate O-methyltransferase activity
           |__protein-glutamine N-methyltransferase activity 5 rec.
           |   |__histone H2AQ104 methyltransferase activity 2 rec.
           |   |__peptide chain release factor N(5)-glutamine methyltransferase activity 1 rec.
           |__protein-L-histidine N-pros-methyltransferase activity 1 rec.
           |__protein-L-histidine N-tele-methyltransferase activity 2 rec.
           |__protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 1 rec.
           |__putrescine N-methyltransferase activity
           |__pyridine N-methyltransferase activity
           |__quercetin 3-O-methyltransferase activity
           |__RNA 5'-gamma-phosphate methyltransferase activity
           |__RNA cap trimethylguanosine synthase activity 1 rec.
           |__rRNA methyltransferase activity 21 rec.
           |   |__rRNA (adenine) methyltransferase activity(+) 7 rec.
           |   |__rRNA (cytosine) methyltransferase activity(+) 5 rec.
           |   |__rRNA (guanine) methyltransferase activity(+) 3 rec.
           |   |__rRNA (pseudouridine) methyltransferase activity(+) 1 rec.
           |   |__rRNA (uridine) methyltransferase activity(+) 3 rec.
           |__S-adenosylmethionine-homocysteine S-methyltransferase activity 2 rec.
           |__sarcosine N-methyltransferase activity
           |__site-specific DNA-methyltransferase (adenine-specific) activity
           |__site-specific DNA-methyltransferase (cytosine-N4-specific) activity
           |__sterol 24-C-methyltransferase activity
           |__tellurite methyltransferase activity
           |__tetrahydrocolumbamine 2-O-methyltransferase activity
           |__thioether S-methyltransferase activity
           |__thiol S-methyltransferase activity
           |__thiopurine S-methyltransferase activity
           |__trans-aconitate 2-methyltransferase activity
           |__trans-aconitate 3-methyltransferase activity
           |__tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity
           |__tRNA (adenine) methyltransferase activity 4 rec.
           |   |__tRNA (adenine(9)-N1)-methyltransferase activity 1 rec.
           |   |__tRNA (adenine(22)-N1)-methyltransferase activity
           |   |__tRNA (adenine(37)-C2)-methyltransferase activity
           |   |__tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
           |   |__tRNA (adenine(58)-N1)-methyltransferase activity 1 rec.
           |   |__tRNA (adenine-N6)-methyltransferase activity
           |   |__tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity 2 rec.
           |__tRNA (cytidine) methyltransferase activity 7 rec.
           |   |__tRNA (cytidine(32)-2'-O)-methyltransferase activity 1 rec.
           |   |__tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase activity
           |   |__tRNA (cytidine(34)-2'-O)-methyltransferase activity 1 rec.
           |   |__tRNA (cytidine(56)-2'-O)-methyltransferase activity
           |   |__tRNA (cytidine-3-)-methyltransferase activity 1 rec.
           |   |__tRNA (cytidine-5-)-methyltransferase activity 3 rec.
           |__tRNA (guanine) methyltransferase activity 10 rec.
           |   |__tRNA (guanine(6)-N2)-methyltransferase activity
           |   |__tRNA (guanine(7)-N2)-methyltransferase activity
           |   |__tRNA (guanine(10)-N2)-dimethyltransferase activity
           |   |__tRNA (guanine(10)-N2)-methyltransferase activity 1 rec.
           |   |__tRNA (guanine(18)-2'-O)-methyltransferase activity 1 rec.
           |   |__tRNA (guanine(26)-N2)-dimethyltransferase activity 1 rec.
           |   |__tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity
           |   |__tRNA (guanine(27)-N2)-dimethyltransferase activity
           |   |__tRNA (guanine(37)-N1)-methyltransferase activity 1 rec.
           |   |__tRNA (guanine(46)-N7)-methyltransferase activity 2 rec.
           |   |__tRNA (guanosine(9)-N1)-methyltransferase activity 2 rec.
           |   |__tRNA (guanosine(34)-2'-O)-methyltransferase activity 2 rec.
           |__tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 1 rec.
           |__tryptophan 2-C-methyltransferase activity
           |__tyramine N-methyltransferase activity
           |__uroporphyrin-III C-methyltransferase activity
           |__vitexin 2''-O-rhamnoside 7-O-methyltransferase activity
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Synonyms
  • "S-adenosyl methionine-dependent methyltransferase activity" EXACT
    "SAM-dependent methyltransferase activity" EXACT
Secondary IDs
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